Metabolism

Cytochrome P-450 3A3/4 Isoenzyme

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Cytochrome P-450 3A3/4 Isoenzyme, Cytochrome P-450 3A3, Cytochrome P-450 3A4, CYP3A3, CYP3A4, CYP3A Inducer, CYP3A Inhibitor, CYP3A Substrate, CYP3A3/4 Inducer, CYP3A3/4 Inhibitor, CYP3A3/4 Substrate

  • Background
  1. Responsible for majority of P-450 Drug Interactions
  2. Accounts for 40 to 60% of hepatic P-450 isoenzymes
  3. Also present in intestinal epithelium
  • Interactions
  • Inducer of CYP 3A3/4