Pharm

Ergotamine

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Ergotamine, Wigraine

  • Indications
  1. Migraine Abortive Management
  • Dosing
  1. Sublingual
    1. One tab SL
    2. Repeat in 1/2 hour prn
    3. Maximum: 3/day or 6/week
    4. Oral tablets available
  2. Rectal Suppository (Wigraine)
    1. One rectally at Headache onset
    2. May repeat hourly
    3. Maximum: 2 suppositories per day or 12 per month
    4. Limit no more than 2 days per week
    5. May use for Menstrual Migraine
  • Adverse Effects
  1. Nausea, Vomiting
    1. Use Antiemetic
  2. Rebound Headache
  3. Occluded vessel in Overdose
    1. Overdose levels
      1. Daily use exceeds 6 mg
      2. Weekly use exceeds 10 mg
    2. Potentiated by
      1. Beta Blockers
      2. Dopamine
      3. Fever
      4. Liver Disease