-
Insomnia
- Short-term use only
- Adult: 0.125 to 0.25 mg orally at bedtime for 7 to 10 days as needed
- Elderly: 0.125 mg orally at bedtime for 7 to 10 days as needed
- Maximum: 0.5 mg at bedtime (0.25 mg is sufficient in most patients)
-
Half-Life: 1.5-5.5 hours
- Metabolized by CYP3A4 to inactive metabolites
- Reports of Psychosis and Violence
- Associated with high dose Halcion (>1 mg)
- Likely to be as safe as other Benzodiazepines
- (2019) Med Lett Drugs Ther 61(1578): 121-6
- (2020) Presc Lett, Resource #361206, Appropriate Use of Benzodiazepines
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 55
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
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