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Restrictive Lung Disease

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Restrictive Lung Disease, Restrictive Pulmonary Disease, Restrictive Lung Function

  • See Also
  1. Pulmonary Function Test
  2. Lung Volumes
  3. Diffusing Capacity
  4. Inhalation Challenge Test
  5. Exercise Spirometry
  6. Functional Residual Capacity
  7. Vital Capacity
  8. Peak Expiratory Flow Rate (PEFR)
  9. Spirometry Lower Limit of Normal (PFT LLN)
  10. Obstructive Lung Disease
  1. Ankylosing Spondylitis
  2. Kyphosis
  3. Morbid Obesity
  4. Scoliosis
  • Causes
  • Medications
  1. Amiodarone
    1. Pulmonary fibrosis
  2. Methotrexate
    1. Pulmonary fibrosis
    2. Hypersensitivity Pneumonitis
  3. Nitrofurantoin
    1. Acute Nitrofurantoin Pulmonary Toxicity
  1. See Interstitial Lung Disease
  2. Asbestosis
  3. Berylliosis
  4. Eosinophilic Pneumonia
  5. Hypersensitivity pneumonitis
  6. Idiopathic Pulmonary Fibrosis
  7. Sarcoidosis
  8. Silicosis (late stage)
  • Causes
  • Neuromuscular
  1. Amyotrophic Lateral Sclerosis (ALS)
  2. Guillain-Barre Syndrome
  3. Muscular Dystrophy
  4. Myasthenia Gravis
  1. See Pulmonary Function Test
  2. Criteria
    1. FEV1 to FVC Ratio >0.7 (or >LLN or for children>85% of predicted) AND
    2. FVC < LLN (or for age 5 to 18 years old, <80% of predicted)
  3. Assess Severity
    1. FVC over 80%: Normal
    2. FVC over 60%: Mild Restrictive Lung Disease
    3. FVC over 40-50%: Moderate Restrictive Lung Disease
    4. FVC under 50%: Severe Restrictive Lung Disease
  4. Additional testing
    1. Diffusing lung capacity for Carbon Monoxide (DLCO)
    2. DLCO to alveolar volume ratio
    3. Expiratory Reserve Volume
  5. Precaution
    1. Note that mixed obstructive-Restrictive Lung Disease can also occur
  • References
  1. Johnson (2014) Am Fam Physician 89(5): 359-66 [PubMed]