Pharm

Acute Nitrofurantoin Pulmonary Toxicity

search

Acute Nitrofurantoin Pulmonary Toxicity

  • See Also
  1. Nitrofurantoin
  • Epidemiology
  1. More common in younger patients
  • Symptoms
  1. Fever
  2. Cough
  3. Chest Pain
  4. Fever
  5. Rash (variably present)
  • Labs
  1. Complete Blood Count
    1. Eosinophilia
  1. Diffuse Pulmonary Infiltrates
  • Differential Diagnosis
  1. Idiopathic Pulmonary Fibrosis
    1. Occurs with Nitrofurantoin and GFR <30 ml/min
  • Management
  1. Immediate Nitrofurantoin cessation (resolves on stopping Nitrofurantoin)
  2. Consider Corticosteroids
  • References
  1. Vahid (2006) Internet J Pulm Med 6(2): 1531-2984