- Pregnancy Categories will be replaced on medication bottles with specific warnings and precautions by 2020 in U.S.
- http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm425317.htm
- Although FDA Pregnancy Categories are no longer FDA designated, they are included here
- As of 2018, succinct guidance (to replace ABCDX) on specific drugs in pregnancy is lacking
- No risk in controlled animal studies
- Iron Sulfate - Not in Briggs (1998)
- Anticoagulants
- Small risk in controlled animal studies
- Antiplatelet Medications
- Clopidogrel (Plavix) - not in Briggs (1998)
- Dipyridamole (Persantine)
- Ticlopidine (Ticlid) - not in Briggs (1998)
- Chemotherapeutics
- Strong evidence of risk to the human fetus
- Chemotherapeutics
- Miscellaneous Agents
- EDTA - Not in Briggs (1998)
- Penicillamine
- Anticoagulants
- Very high risk to the human fetus
- Leuprolide (Lupron)
- Aminopterin
- Briggs (1998) Drugs in Pregnancy and Lactation, 5th ed
- Larimore (2000) Prim Care 27(1):35-53 [PubMed]