Pharm
Estrostep
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Estrostep
See Also
Oral Contraceptive
Oral Contraceptive Drug Interaction
Oral Contraceptive Selection
Oral Contraceptive Side Effect Management
Oral Contraceptive-Related Uterine Bleeding Management
Preparations (Norethindrone Acetate / Ethinyl Estradiol)
Estrostep (1 / 20 - 30 - 35)
Components
Norethindrone Acetate
1 mg (see preparation above)
Ethinyl Estradiol
20 ug - 30 ug - 35 ug
Effects
Relative
Progestational Activity
: 1.2 (high)
Estrogenic Activity
: 16 (low)
Androgenic Activity
: 0.53 (high)
Pill associated problems
Indications to switch to
Ortho Novum 1/35
Acne Vulgaris
(lower androgen)
Indications to switch to
Ortho Cyclen
Increased Appetite (lower
Progestin
)
Major Depression
provoked (lower
Progestin
)
Indications to switch to
Lo/Ovral
Break-through bleed days 1-9 (more
Estrogen
)
Break-through bleed all of month (more
Estrogen
)
Menses
too light (more
Estrogen
, less
Progestin
)
Indications to switch to
Loestrin 1.5/30
Libido decreased (more androgen)
Break-through bleed days 10-21 (more
Progestin
)
Heavy
Menses
(more
Progestin
or less
Estrogen
)
Dysmenorrhea
or
Menstrual Cramps
(more
Progestin
)
Indications to switch to
Loestrin 1/20
Breast
Tenderness or engorgement (lower
Estrogen
)
Headache
s (lower
Estrogen
)
Moodiness (less
Estrogen
or more
Progestin
)
Weight gain (less
Estrogen
or more
Progestin
)
References
Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
Dickey (1998) Managing Contraceptive Pill Patients
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