Lab

Troponin T

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Troponin T, Troponin T Assay

  • See Also
  1. Troponin
  2. Troponin I
  3. Ultrasensitive Troponin T
  4. Serum Cardiac Markers
  • Epidemiology
  1. Test Sensitivity: 94% of Myocardial Infarctions
  2. Test Specificity: Low (22% have Unstable Angina)
    1. See Troponin for false possible causes
  1. Serum levels increase within 4-8 hours of MI onset
  2. Serum levels peak at 12 to 48 hours
  3. Serum levels are elevated for 4-10 days after MI
  • Advantages
  1. Highly sensitive for detecting Myocardial Infarction
  2. Level may also help to risk stratify afterward
  3. Qualitative test run in 10 minutes
  • Disadvantage
  1. Less specific than Troponin I
    1. Elevated in Unstable Angina
    2. Elevated in Chronic Renal Failure
  2. Levels stay elevated for days
    1. Unable to time acute coronary event
  • References
  1. Lindahl (1996) Circulation 93:1651-7 [PubMed]
  2. Stubbs (1996) Circulation 94:1291-7 [PubMed]