Lab

Troponin I

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Troponin I, Troponin I Assay

  • See Also
  1. Ultrasensitive Troponin T
  2. Troponin
  3. Serum Cardiac Markers
  • Epidemiology
  1. Sensitivity: 100% of Myocardial Infarctions
  2. Specificity: Low (36% have Unstable Angina)
    1. See Troponin for false possible causes
  1. Serum levels increase within 4-8 hours of MI onset
  2. Serum levels peak at 12 to 48 hours
  3. Serum levels are elevated for 4-10 days after MI
  • Advantages
  1. More specific than Troponin T
  2. Not falsely elevated in Chronic Renal Failure
  1. Obtain 2 Troponin values 6 hours apart
  • Interpretation
  1. Level >1.0 to 1.2 suggestive of Myocardial Infarction
  2. Two negative values 3-6 hours apart
    1. Predicts low likelihood of Acute Coronary Syndrome