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Benzodiazepine Equivalents
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Benzodiazepine Equivalents
, Barbiturate Equivalents, Sedative Equivalents
Indications
Benzodiazepine Withdrawal
Barbiturate withdrawal
Sedative
withdrawal
Preparations
Benzodiazepine
s Equivalents
Alprazolam
(
Xanax
)
Alprazolam
0.5 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x20
Phenobarbital
= Dose x30
Chlordiazepoxide
(
Librium
, Limbitrol)
Chlordiazepoxide
25 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x0.4
Phenobarbital
= Dose x1.2
Clonazepam
(
Klonopin
)
Clonazepam
0.5 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x20
Phenobarbital
= Dose x7.5
Flurazepam
(
Dalmane
)
Flurazepam
15-30 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x0.33
Phenobarbital
= Dose x2.0
Halazepam
(
Paxipam
)
Halazepam
20 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x0.5
Phenobarbital
= Dose x0.75
Lorazepam
(
Ativan
)
Lorazepam
1 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x10
Phenobarbital
= Dose x15.0
Oxazepam
(
Serax
) 60 mg
Oxazepam
20 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x0.5
Phenobarbital
= Dose x3.0
Temazepam
(
Restoril
)
Temazepam
20 mg is equivalent to 10 mg
Diazepam
Valium
= Dose x0.5
Phenobarbital
= Dose x3.0
Preparations
Barbiturate Equivalents
Butabarbital (Butisol)
Valium
= Dose x0.1
Phenobarbital
= Dose x0.3
Pentobarbital
(
Nembutal
)
Valium
= Dose x0.1
Phenobarbital
= Dose x0.3
Secobarbital
(Seconal)
Valium
= Dose x0.1
Phenobarbital
= Dose x0.3
Phenobarbital
Valium
= Dose x0.33
Preparations
Miscellaneous Sedative Equivalents
Glycerol
:
Meprobamate
(
Equanil
)
Valium
= Dose x0.025
Phenobarbital
= Dose x0.075
Piperidinedione: Glutethimide (Doriden)
Valium
= Dose x0.04
Phenobarbital
= Dose x0.12
Quinazoline:
Methaqualone
Valium
= Dose x0.03
Phenobarbital
= Dose x0.1
References
Ashton (2005) Curr Opin Psychiatry 18:249-55 [PubMed]
Tauseef (2012) BJMP 5(1): a501 [PubMed]
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