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Barbiturate Abuse

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Barbiturate Abuse, Barbiturate withdrawal

  • See Also
  1. Chemical Dependency
  2. Substance Abuse Evaluation
  • Class
  1. Sedative-Hypnotic
  • Preparations
  • Forms
  1. Phenobarbital
  2. Nembutal
  3. Seconal
  4. Amytal
  • Preparations
  • Street Names
  1. Blue Devils
  2. Yellow Jackets
  3. Blue Heavens
  4. Downers
  5. Barbs
  • Pharmacokinetics
  1. Seconal (30-500 mg): 6-8 hours duration
  • Signs
  • Withdrawal
  1. Seizure
  2. Delirium
  1. Supportive care with airway management for CNS Depression (similar to Benzodiazepines)
  2. Urine Alkalinization with Sodium Bicarbonate
  1. See also Barbiturate Equivalents
  2. Pentobarbital challenge (shorter half life)
    1. Start: 200 mg Pentobarbital
    2. Then: 100 q2 hours until mildly intoxicated
  3. Switch to Phenobarbital
    1. Convert: 30 mg Phenobarbital = 100 mg Pentobarbital
    2. Decrease Phenobarbital by 10% per day