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Methoxy Polyethyelene Glycol Epoetin Beta

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Methoxy Polyethyelene Glycol Epoetin Beta, Mircera

  • See Also
  1. Erythropoietin
  • See Also
  1. Erythropoietin
  • Indications
  1. See Erythropoietin
  2. Anemia of Chronic Renal Failure (Hemoglobin <10 g/dl)
  3. Not FDA approved for use in cancer patients
  • Contraindications
  1. See Erythropoietin
  • Mechanism
  1. See Erythropoietin
  • Precautions
  1. Not a substitute for Blood Products in acute severe, symptomatic Anemia
  2. Avoid Hemoglobin targets above 11 g/dl (higher risk of cardiovascular and thrombotic events)
    1. Use the lowest effective dose
  3. Iron Supplementation if needed
    1. Check for Iron Deficiency before administration
  • Medications
  1. Available in single-dose prefilled syringes 30 to 360 mcg
  • Dosing
  • Adult
  1. Start 0.6 mcg/kg IV or SQ every 2 weeks
  2. Indicated for Hemoglobin <10 g/dl
  3. Stop if Hemoglobin >10 g/dl (or >11 g/dl if on Hemodialysis)
  • Dosing
  • Child
  1. See other references (see resources below)
  2. Dose is based on conversion of stable Hemoglobin on other Erythropoietin product to Mircera
  3. Every 4 week dosing
  • Adverse Effects
  1. See Erythropoietin
  • Safety
  1. Unknown safety in pregnancy
  2. Unknown safety in Lactation
  • Resources
  1. Methoxy Polyethyelene Glycol Epoetin Beta (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=22c56f2a-f73c-60e7-e054-00144ff88e88