Lab

Iron Saturation

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Iron Saturation, Serum Transferrin Saturation, Transferrin Saturation, Transferrin Iron Saturation, Serum Iron to TIBC Ratio

  • Calculation
  1. TFS = 100 x Serum Iron (ug/dl) / TIBC (ug/dl)
  • Normal
  1. Range: 15% to 55%
  • Decreased
  1. Chronic Iron Deficiency Anemia
  2. Chronic infection
  3. Advanced malignancy
  4. Collagen-Vascular Disease
  5. Uremia
  6. Third trimester of pregnancy
  • Increased
  1. Hemochromatosis and other Iron Overload
  2. Hemolytic Anemia
  3. Starvation
  4. Nephrotic Syndrome
  5. Cirrhosis
  6. Acute Viral Hepatitis
  7. Thalassemia minor
  8. Megaloblastic Anemia
  9. Aplastic Anemia or Sideroblastic Anemia
  • References
  1. Ravel (1995) Clinical Lab Medicine, Mosby, p. 662