- Transferrin carries 2 iron atoms per molecule
- Transferrin is normally 30% bound to iron
- TIBC reflects a measurement of serum Transferrin
- Measured by saturating all available binding sites
- Normal
- Range: 250-460 ug/dl
- Increased TIBC
- Iron Deficiency Anemia
- Third trimester Pregnancy
- Polycythemia Vera
- Decreased TIBC