Pharm

Danazol

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Danazol

  • Indications
  • Pathophysiology
  1. Synthetic isoxazol derivative of ethisterone
  2. Inhibits gonadotropic secretion
  3. Prevents Menstrual Bleeding
  4. Mildly androgenic
  • Dosing
  1. Danazol 400-600 mg qd
  • Efficacy
  1. Expensive ($100/month)
  2. Same rate of pregnancy as with Provera or Surgery
  • Adverse Effects
  • Androgenic effects
  1. Acne Vulgaris
  2. Flushes
  3. Sweats
  4. Edema
  5. Libido changes