- Hair-AN Acronym
- Hyperandrogenism (HA)
- Insulin Resistance (IR)
- Acanthosis Nigricans (AN)
- Primary abnormality
- Insulin Resistance causes increased Insulin
- Secondary abnormality
- Excess androgen secretion from ovaries
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General lab testing
- Complete Blood Count (CBC)
- Thyroid Stimulating Hormone (TSH)
- Serum Prolactin
- Serum Electrolytes (Chem7)
- Labs associated with Insulin Resistance
- Fasting Serum Glucose
- Consider Glucose Tolerance Test
- Labs associated with Androgen Excess
- See Hyperandrogenism
-
General Measures
- Weight loss
- See Hirsutism
- Gonadotropin suppression
- Oral Contraceptives (low Androgenic Activity)
- Anti-androgens
- Spironolactone (Aldactone) 50 to 100 mg po bid
- Flutamide (Eulexin)
- Risk of hepatotoxicity
- Finasteride (Proscar) 5 mg per day
-
Insulin Resistance Modifier
- Glucophage (Metformin) 500 - 850 mg PO qd to bid