- Peptic Ulcer Disease
- Gastroesophageal Reflux
- Erosive Esophagitis
- Zollinger-Ellison Syndrome
- Hypersensitivity to Proton Pump Inhibitors
- Severe liver disease
- Limit maximum dose to 30 mg/day in moderate liver Impairment
- Dexlansoprazole (Dexilant) is the active L-Isomer of Lansoprazole (Prevacid)
- Background
- Take regardless of timing of meal
- May open capsule and sprinkle on applesauce or water (may be given via NG tube)
- See Proton Pump Inhibitor for Discontinuation or Deprescribing
- Generic, but not OTC as of 2022
- Adults and age >=12 years
- Symptomatic Nonerosive Gastroesophageal Reflux
- Take 30 mg orally daily
- Erosive Esophagitis
- Take 60 mg orally daily for up to 8 weeks, then 30 mg orally daily for up to 6 months
- Symptomatic Nonerosive Gastroesophageal Reflux
- Pregnancy Category B
- Unknown safety in Lactation
- Dexlansoprazole (DailyMed)