Diarrhea

Chronic Inflammatory Diarrhea

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Chronic Inflammatory Diarrhea, Inflammatory Diarrhea

  • See Also
  1. Diarrhea
  2. Chronic Fatty Diarrhea (Diarrhea due to Malabsorption)
  3. Chronic Watery Diarrhea (Secretory or Osmotic Diarrhea)
  4. Acute Inflammatory Diarrhea
  5. Inflammatory Bowel Disease
  6. Infectious Diarrhea
  7. Drug-Induced Diarrhea
  8. Diarrhea in Cancer
  9. Diarrhea in Children
  10. Diarrhea in Pregnancy
  11. Diarrhea in HIV
  • Definitions
  1. Chronic Inflammatory Diarrhea
    1. Bloody or purulent stool seen in Inflammatory Bowel Disease and infectious enteritis
  • Causes
  1. See Acute Inflammatory Diarrhea
  2. Inflammatory Bowel Disease
    1. Ulcerative Colitis
    2. Crohn's Disease
    3. Diverticulitis
  3. Invasive Infections
    1. Bacterial Infections
      1. Clostridium difficile
      2. Mycobacterium tuberculosis
      3. Yersinia enterocolitica
    2. Viral Infection (ulcerative)
      1. Cytomegalovirus (CMV)
      2. Herpes Simplex Virus (HSV)
    3. Parasitic Infection
      1. Giardiasis causes Chronic Fatty Diarrhea (Diarrhea due to Malabsorption)
      2. Amebiasis
      3. Strongyloides
      4. Ascaris lumbricoides (roundworm infection)
  4. Ischemic Colitis (typically acute)
  5. Radiation Colitis
  6. Malignancy
    1. Colon Cancer
    2. Lymphoma
    3. Villous adenocarcinoma
  • Labs
  1. Stool Leukocytes with gross blood and pus present
  2. Fecal Calprotectin level
    1. Highly sensitive and specific for Inflammatory Bowel Disease
  • Diagnostics
  1. Colonoscopy with biopsy
  • References
  1. Schiller in Feldman (2002) Sleisenger GI, p. 136
  2. Burgers (2020) Am Fam Physician 101(8): 472-80 [PubMed]