Lab

Fecal Calprotectin

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Fecal Calprotectin

  • Indications
  1. Suspected Inflammatory Bowel Disease
  • Mechanism
  1. Indicator of fecal Leukocyte activity
  • Protocol
  1. Calprotectin is stable in stool samples at room Temperature for up to 1 week
  • Interpretation
  1. Negative test suggests diagnoses other than Inflammatory Bowel Disease are more likely
  2. Positive test requires Colonoscopy for confirmation
  1. Test Sensitivity: 93%
  2. Test Specificity
    1. Adults: 96%
    2. Children and Adolescents: 76%
  • References
  1. Schoepfer (2010) Am J Gastroenterol 105(1): 162-9 [PubMed]
  2. van Rheenen (2010) BMJ 341:c3369 [PubMed]