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Myocardial Perfusion Imaging with Adenosine

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Myocardial Perfusion Imaging with Adenosine, Stress Imaging with Adenosine, Pharmacologic Stress Test with Adenosine, Adenosine Nuclear Test, Adenosine Cardiolite, Pharmacologic Stress Test with Regadenoson, Lexiscan Cardiolite

  • See Also
  1. Exercise Stress Test
  2. Stress Imaging
  3. Pharmacologic Stress Test
  4. Stress Echocardiogram
  5. Stress Myocardial Perfusion Imaging
  • Definition
  1. Myocardial Perfusion Imaging using Adenosine (or Regadenoson/Lexiscan)
  • Approach
  1. Hold nitrates (Nitroglycerin) on day of the test
  2. Hold methylzanthines 24 hours before test
    1. Theodur
    2. Aminophylline
    3. Dipyridamole
  • Preparations
  1. Adenosine or
  2. Regadenoson (Lexiscan)
    1. Longer half life than Adenosine
    2. Can be adminstered as bolus instead of continuous infusion
  • Advantages
  1. Short duration of Adenosine action (<3 seconds)
  2. Vasodilator increases coronary flow 5x
  3. More sensitive than Dobutamine (but less specific)
  4. ST Depression specific for serious disease
    1. Left main Coronary Artery Disease
    2. Three-vessel Coronary Artery Disease
  • Indications
  1. Left Bundle Branch Block
  2. Paced Rhythm
  3. WPW Syndrome
  • Contraindications
  1. Asthma
  2. Severe Chronic Obstructive Pulmonary Disease (COPD)
  3. Concurrent medication use
    1. Dipyridamole
    2. Aggrenox
    3. Theophylline
    4. Caffeine prior to test (e.g. Coffee, Chocolate)