Procedure
Arterial Cannulation
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Arterial Cannulation
, Arterial Line
See Also
Arterial Puncture
Indications
Critically Ill Patient
Serial
Arterial Blood Gas
monitoring (e.g.
ARDS
, esp. if >4 samples needed in 24 hours)
Continuous
Blood Pressure Monitoring
optimized for accuracy
Accurate systolic and diastolic
Blood Pressure
s for titrated vasoactive medications in shock
Cardiac Arrest
Hypertensive Emergency
Intracranial Hemorrhage
Aortic Dissection
Other hemodynamic monitoring parameters may be estimated electronically (based on wave form)
Cardiac Output
Stroke Volume
Pulse Pressure
Variation
Contraindications
Affected limb injury (
Trauma
,
Fracture
s, burns,
Cellulitis
)
Raynaud Syndrome
Thromboangiitis Obliterans
(Buerger Disease)
Coagulopathy
Ultrasound
guidance of a 6 Fr catheter may be safely placed if INR<3 and
Platelet Count
>20k
Precautions
Never use arterial catheters for medication or fluid infusions
Monitor line continuously
Alarms that would indicate open catheter (with blood loss)
Inspect for ischemic limb or infection
Remove catheter immediately if these occur
Remove catheters as soon as they are no longer needed
Must calibrate catheter and transducer first at heart level
As with
Blood Pressure
s in general, normal arterial pressure does not exclude hypoperfusion
Compensatory
Vasocon
striction may mask hypoperfusion until precipitous drop
Use other measures (e.g.
IVC Ultrasound for Volume Status
) to further evaluate vascular status
Abnormal pressure readings from catheter should be confirmed with manual
Blood Pressure
readings
Waveform may be distorted by vascular and transducer changes
Mean arterial pressure typically remains accurate despite waveform distortion
Preparation
Arterial Line Sites (in order of preference)
Radial artery (preferred)
Lowest rate of complications (4%)
Lowest failure rate (5%)
Femoral artery (requires longer catheter)
Higher systolic
Blood Pressure
(+5 mmHg) in the femoral Arterial Lines compared with radial artery
Highest risk for complications (12%, including bleeding,
Hematoma
, pseudoaneurysm)
Highest failure rate (30%)
Place the line below the inguinal ligament (compressible)!
Consider in
Unstable Patient
s undergoing active
Resuscitation
efforts
Femoral site may be prepped for both
Femoral Central Line
and Arterial Line
Avoid Brachial artery cannulation (risk of distal hand ischemia)
However good evidence for safety of brachial artery line in cardiac surgery (placed by skilled operators)
Singh (2017) Anesth 126:1066 +PMID: PMID: 28398932 [PubMed]
Other sites
Axillary artery (requires longer catheter)
Dorsalis pedis artery (less reliable reading in adults)
Technique
Preparation for Wrist Arterial Cannulation
Confirm collateral circulation
Ultrasound
may be used to demonstrate pulsatile flow in both ulnar and radial arteries
Modified
Allen Test
has poor correlation and prediction of distal extremity ischemia
Valgimigli (2014) J Am Coll Cardiol 63(18): 1833-41 +PMID: 24583305 [PubMed]
Obtain IV catheter
Needle of 18 or 20 gauge with plastic cannula
Flush with
Heparin
ized saline
Position patients wrist and hand
Ideal wrist flexion to 45 degrees
Patient dorsiflexes wrist over sterile gauze roll (e.g. Kerlix)
Tape palm and upper
Forearm
to arm board
Clean radial entry site
Chlorhexidine
or
Povidone-Iodine
solution (
Betadine
) scrub
Local Anesthetic
at entry site
Small skin wheal (1-2 ml) of
Lidocaine
1-2% WITHOUT
Epinephrine
Do NOT use
Lidocaine
with
Epinephrine
(causes vasospasm, interfering with arterial placement)
Ultrasound
Use high frequency linear probe with sterile probe cover and sterile gel between skin and probe
Transverse probe orientation is adequate (short distance from skin surface to vessel)
Technique
Placing Radial Arterial Line
Optimize first pass success (best chance for successful cannulation)
Sit for the procedure
Take time to identify maximal pulse
Identify radial artery with gentle pressure
Palpate with 2 parallel fingertips (identifies artery orientation)
Initial vasospasm may interfere with vessel identification (may need to wait for vasospasm to subside)
Enter skin just distal to palpated artery site
Entry is 2 cm (1 finger breadth) proximal to the distal wrist crease
Needle angled 30 to 45 degrees toward arm
Slowly advance needle until spontaneous blood enters
After vessel entry, reduce the angle of entry and reconfirm pulsatile blood in catheter
Guidewire
Guidewires are often incorporated into Arterial Line catheter
Guidewire passed into artery
Remove needle
Advance flushed plastic cannula over top of guide wire
Uses modified Seldinger technique
Gentle twisting motion of catheter may be needed to advance catheter fully
Secure catheter to skin
Use 2-0
Silk Suture
Apply transparent dressing
Turn 3-way Stopcock to seal artery
Remove pad under wrist and secure arm board
Technique
Arterial Line Connection and Calibration
Connect transducer and high-pressure infusion set to catheter hub
Transducer should be at the level of the right atrium
Prepare the tubing
Three-way stop cock should be off to patient (and open to the atmosphere)
Catheter tubing is flushed with saline
Remove any air bubbles from the line
Increase pressure in the line using a pressure bag
Zero the monitor
Press zero on the monitor
Once the monitor reads zero
Turn the stopcock to be open to the patient and closed to the atmosphere
Visualize wave form on monitor
Adjust monitor scale as needed to adequately visualize wave form
Adjust patient position as needed so that the transducer remains at right atrium level
Monitoring
A-Line compatible monitors
Continuous reading of systolic and diastolic
Blood Pressure
as well as mean arterial pressure
Requires calibration and special tubing
Disposable monitors
Attach inline to the catheter and have a small digital screen displaying mean arterial pressure
Complications
Arterial Thrombosis
Risk increases with decreasing wrist circumference
Risk increases rapidly in first 24 hours, than slowly
Bleeding Complications (1.8-2.6%)
Hematoma
or line oozing are most common bleeding complications
Open Arterial Line can result in rapid, life-threatening blood loss
Risk Factors
Femoral Arterial Lines are the highest risk for bleeding complications
Multiple attempts at placement
Landmark-based line placement (without
Ultrasound
)
Catheter embolization (e.g. CVA)
Occurs with vigorous
Flushing
of radial catheters
Gentle irrigation with 1-2 ml boluses should be used
Arterial Line infections
Risk increases after 72 hours
Follow same preventive strategies as for
Central Line-Associated Bloodstream Infection
(
CLABSI
)
Arterial Line bloodstream infections occur at the same rate (0.9 to 3.4%) as
CLABSI
Arterial Line bloodstream infections carry the same morbidity and mortality of
CLABSI
Use sterile technique on placement as with
Central Line Placement
Remove catheter at earliest possible time
Provide careful wound and dressing care
Other arterial complications (esp. femoral Arterial Lines)
Pseudoaneurysm
Arteriovenous Fistula
Resources
Arterial Line Placement -
Ultrasound
Guided (Dr. Mellick, Youtube)
https://www.youtube.com/watch?v=VtoVavr0W9k
References
Rutherford (2025) Arterial Line, Hospital Procedures Course
Killu and Sarani (2016) Fundamental
Critical Care
Support, p. 93-114
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