Lab

Urine Leukocyte Esterase

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Urine Leukocyte Esterase, Urine Dipstick Leukocyte Esterase

  • See Also
  1. Urinalysis
  2. Urine Nitrite
  • Mechanism
  1. Neutrophil Granulocytes contain esterases
  2. Positive test suggests pyuria
    1. Dipstick requires 5 minutes to change color
  • Interpretation
  • Normal
  1. Negative
  • Interpretation
  • Positive (Abnormal)
  1. Urinary Tract Infection
  2. Sexually Transmitted Infection
  3. Vaginal contaminant
  1. Inadequate time allowed for dipstick reading (60 to 120 seconds)
  2. Increased Urine Specific Gravity
  3. Urine Glucose present (Glycosuria)
  4. Urine Ketones present (Ketonuria)
  5. Urine Protein present (Proteinuria)
  6. Vitamin C
  7. Enterococcus UTI
  8. Klebsiella UTI
  9. Antibiotics
    1. Cefalexin (Keflex)
    2. Nitrofurantoin (Macrobid)
    3. Tetracycline
    4. Gentamicin
  1. Chlamydia
  2. Ureaplasma urealyticum
  3. Balanitis
  4. Bladder Cancer
  5. Nephrolithiasis
  6. Tuberculosis
  7. Urinary tract foreign body
  8. Glomerulonephritis
  9. Medications (Corticosteroid, Cytoxan)
  10. Methenamine
  • References
  1. Hitzeman (2022) Am Fam Physician 106(1): 27-35 [PubMed]
  2. Simerville (2005) Am Fam Physician 71(6): 1153-62 [PubMed]