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Medication Causes of Neuropathy

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Medication Causes of Neuropathy, Drug-Induced Polyneuropathy, Peripheral Neuropathy Due to Medications

  • See Also
  1. Symmetric Neuropathy
  2. Asymmetric Neuropathy
  3. Peripheral Neuropathy
  • Causes (Axonal and sensory effects unless otherwise noted)
  1. Neuropsychiatric Medications
    1. Amitriptyline
    2. Levodopa
    3. Lithium (sensorimotor)
    4. Phenytoin
  2. Antimicrobial Medications
    1. Antiretrovirals
    2. Chloroquine (demyelinating)
    3. Dapsone
    4. Didanosine
    5. Ethambutol
    6. Interferon alfa
    7. Isoniazid
    8. Nitrofurantoin (sensorimotor)
    9. Metronidazole
    10. Stavudine
    11. Antifungal Triazoles (e.g. Fluconazole)
  3. Cardiovascular Medications
    1. Amiodarone (sensorimotor)
    2. Digoxin
    3. Hydralazine
    4. Procainamide (demyelinating)
    5. Statins (e.g. Simvastatin)
  4. Chemotherapy Medications
    1. Bortezomib (Velcade)
    2. Cisplatin
    3. Oxaliplatin
    4. Paclitaxel
    5. Thalidomide
    6. Vincristine (sensorimotor)
  5. Heavy Metals
    1. Arsenic Poisoning
    2. Gold
    3. Lead Poisoning
    4. Mercury Poisoning
    5. Thallium
  6. Other Toxins
    1. Acrylamide
    2. Carbon Disulfide
    3. Ethylene Oxide
  7. Miscellaneous
    1. Cimetidine
    2. Colchicine
    3. Disulfiram
    4. Misoprostol or Cytotec (motor)
  • References
  1. Azhary (2010) Am Fam Physician 81(7): 887-92 [PubMed]
  2. Castelli (2020) Am Fam Physician 102(12): 732-9 [PubMed]