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Respiratory Panel
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Respiratory Panel
, Respiratory Bacteria and Virus PCR, BioFire Respiratory Panel
Background
Respiratory Panels are PCR tests (often point-of-care) that test for multiple
Bacteria
and viral
Antigen
s
May decrease the use of antibiotics (or broad spectrum antibiotics) in the ambulatory, emergency and hospital setting
Consider when other testing (cxr,
Influenza
, covid, RSV) in acute respiratory illness is non-diagnostic
However, benefits of testing are mixed against the test costs (>$400 in 2023 and not consistently reimbursed)
Coinfection is not excluded and even when pathogen is identified, antibiotics are often continued
Viral pathogen identification has not consistently resulted in less antibiotic use
Labs
BioFire Respiratory Panel 2.1
Test Sensitivity
is high (95 to 100% except where otherwise noted)
Virus
es (19)
Adenovirus
Coronavirus (6 strains including Covid,
MERS
)
Human
Metapneumovirus
Human
Rhinovirus
and enterovirus
Influenza
(
Influenza
B and various
Influenza
A strains)
Parainfluenza (4 strains)
Respiratory Syncytial Virus
(RSV)
Bacteria
Bordatella
Pertussis
(
Test Sensitivity
66%)
Bordatella Parapertussis (
Test Sensitivity
85%)
Chlamydia pneumoniae
Mycoplasma pneumoniae
References
Bennett (2023) Am Fam Physician 108(2): 189-91
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