- FDA-Approved
- Off-Label
- Behcet's Disease (Meningoencephalitis, Uveitis)
- Membranous Nephropathy
- Ovarian Cancer
- See Alkylating Agent
- Antineoplastic aromatic nitrogen mustard
- As with other Alkylating Agents (and nitrogen mustards), cross-links DNA
- Chlorambucil Tablets (Leukeran): 2 mg
- See other references for disease specific dosing protocols
- Alopecia
- Bone Marrow Suppression
- Impaired future fertility
- Secondary Malignancy
- Seizures
- Avoid in Lactation
- Pregnancy Category D (avoid)
- Use reliable Contraception
- Monitoring
-
Live Vaccines
- Avoid while on Chlorambucil
- Chlorambucil Tablet (DailyMed)