AIDS-Defining Illness


AIDS-Defining Illness, AIDS Defining Illness, AIDS Indicator Condition, Malignancy in HIV, Cancer in HIV

  • Associated Conditions
  • Infectious
  1. See Opportunistic Infections in HIV
  2. Bacterial Pneumonia that recurs for at least two episodes in 12 months
  3. Candidiasis of the Bronchopulmonary Tract (Bronchi, trachea, lungs) or Esophageal Candidiasis
  4. Coccidioidomycosis (disseminated or extrapulmonary)
  5. Extrapulmonary Cryptococcus
  6. Chronic intestinal Cryptosporidium (persistent >1 month)
  7. Cytomegalovirus infection (beyond liver, Spleen and Lymph Nodes) or CMV Retinitis
  8. Herpes Simplex Virus (chronic HSV ulcer present >1 month, HSV Bronchitis, HSV pneumonitis, or HSV Esophagitis)
  9. Histoplasmosis (diseminated or extrapulmonary)
  10. Isosporiasis (Chronic intestinal present >1 month)
  11. Mycobacterium Avium Complex disease
  12. Mycobacterium kansaii
  13. Mycobacterium tuberculosis (pulmonary or extrapulmonary)
  14. Pneumocystis Pneumonia (Pneumocystis jiroveci replaces previously named Pneumocystis carinii or PCP)
  15. Salmonella Sepsis
  • Associated Conditions
  • Cancer
  1. Invasive Cervical Cancer
  2. Kaposi Sarcoma
  3. HIV-related Wasting Syndrome
    1. Weight loss >10% with more than 1 month of fever and two or more loose stools daily
  4. HIV related Lymphoma
    1. Burkitt Lymphoma
    2. Immunoblastic Lymphoma
    3. Primary CNS Lymphoma
  • Associated Conditions
  • Neurologic
  • Resources
  1. AETC National Resource Center
    1. http://www.aids-ed.org/aidsetc?page=cg-205_hiv_classification
  2. (2007) WHO Cased Definitions of HIV for surveillance and revised clinical staging and immunological Classification of HIV-related disease in adults and children
    1. http://www.who.int/hiv/pub/guidelines/HIVstaging150307.pdf