- Functional Constipation
- Colonoscopy Preparation
- Magnesium salt Osmotic Laxatives
- Poorly absorbed, hyperosmolar agents
- Avoid longterm use due to Electrolyte loss risk
- These agents are typically used once as part of a bowel regimen
-
General
- Patients should have immediate access to toilet for at least 6 hours after taking Magnesium Citrate
- Adult (and age >12 years)
- Full dose: Take 8 to 10 ounces (240 to 300 ml, 1 bottle) orally divided once or twice for 1 day
- Half dose: Take 5 oz (150 ml, 1/2 bottle) orally once
- Child (age 2 to 12 years)
- Age 2 to 5 years: 1 to 3 ml/kg/day divided once or twice for 1 day
- Age 6 to 11 years: 4 ml/kg (up to 200 ml) OR 100 to 150 ml divided once or twice for 1 day
- Absorption of up to 30% of Magnesium Citrate dose
- Rapid onset within 3 hours
- Patients should have immediate access to toilet for at least 6 hours after taking Magnesium Citrate
- Hypermagnesemia (in patients with Renal Failure)
- Pregnancy Category B
- Unknown Safety in Lactation
- Decreases absorption of other drugs
-
CNS Depressants
- Magnesium Citrate may have additive effects with increased CNS depression
- Magnesium Citrate (DailyMed)
- (2023) Management of Constipation, Presc Lett, #390108
- Hamilton (2020) Tarascon Pocket Pharmacopoeia