Pharm

Medications Associated With Narrow Angle Glaucoma

search

Medications Associated With Narrow Angle Glaucoma, Drug-Induced Increased Introcular Pressure, Medication-Induced Intraocular Pressure, Medication Causes of Narrow Angle Glaucoma

  • See Also
  1. Glaucoma
  2. Narrow Angle Glaucoma
  3. Intraocular Pressure
  • Background
  1. Medications that dilate the pupil (Mydriasis ) decrease the anterior chamber angle
  2. Narrowed anterior chamber angle may increase Intraocular Pressure, triggering Narrow Angle Glaucoma
  3. Systemic agents may also cause ciliary body edema
  • Causes
  • Eye Preparations
  1. Eye Dilating Drops (Mydriatics)
  2. Ophthalmic Anticholinergic Agents
  • Causes
  • Autonomic Medications
  1. Adrenergic Medications (including Drugs of Abuse)
    1. Nephazoline Intranasal spray
    2. Inhaled Salbutamol
    3. Cocaine
    4. Methamphetamine
  2. Anticholinergic Medications
    1. Oxybutynin
    2. Scopolamine
    3. Benztropine (Cogentin)
    4. Trihexyphenidyl
  3. Antihistamines
    1. Diphenhydramine (Benadryl)
    2. Cimetidine (Tagamet)
  • Causes
  • Neuropsychiatric Medications
  1. Antidepressant Medications
    1. Bupropion
    2. Escitalopram (Lexapro)
    3. Fluoxetine (Prozac)
    4. Tricylic Antidepressants (e.g. Amitriptyline)
    5. Venlafaxine (Effexor)
  2. Antipsychotic Medications
    1. Olanzapine (Zyprexa)
    2. Quetiapine
    3. Thioridazine
  • Causes
  • Sulfa-based Medications
  1. Topiramate
  2. Trimethoprim-Sulfamethoxazole
  • Causes
  • Miscellaneous Medications
  1. Corticosteroids
    1. Risk of Open Angle Glaucoma with longterm Systemic Corticosteroids and especially intra- and periocular Corticosteroids
  2. Mefenamic Acid (Ponstel)
  3. Onabotulinum Toxin A
  4. Promethazine (Phenergan)
  • References
  1. Harris (2023) Am Fam Physician 107(3): 238-46 [PubMed]