Pustule, Hemorrhagic Pustule, Necrotic Pustule

  • Pathophysiology
  1. Typically develop from Vesicles or bullae that fill with pus, or from Hair Follicles or Sweat Glands
    1. May also spontaneous form a non-follicular Pustule
  • Description
  1. Raised, translucent superficial, circumscribed skin lesion
  2. Contains purulent exudate (white, orange, yellow, green)
  3. Follicular Pustules are conical with hair in center
    1. Non-follicular Pustules vary in shape
  • Differential Diagnosis
  • Hemorrhagic Pustules (or Necrotic Pustules)
  • Labs
  1. Gram Stain and culture of pustular discharge (exclude Disseminated Gonorrhea)
  • Examples
  1. Drug Eruption
  2. Acne Vulgaris
  3. Generalized Pustular Psoriasis syndrome
  4. Viral vessicular eruptions may develop into Pustules (e.g. varicella, Herpes Zoster virus, Herpes Simplex Virus)