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Medication Causes of Pericarditis

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Medication Causes of Pericarditis, Pericarditis due to Medications, Drug-Induced Pericarditis

  • Causes
  • Rheumatologic
  1. Agents associated with Lupus-Like Syndrome (Pericarditis is a serositis)
    1. See Drug-induced Lupus
    2. Hydralazine is the most common cause
    3. Other causes include Procainamide, Isoniazid, Minocycline, Terbinafine, Phenytoin
  2. Other rheumatologic agents and Immunosuppressants
    1. Cyclosporine
    2. TNF Inhibitor
  • Causes
  • Neuropsychiatric
  • Causes
  • Miscellaneous
  1. Mesalamine
  2. Granulocyte-Macrophage Colony Stimulating Factor
  3. Thiouracils
  4. SARS-CoV-2 Vaccine
    1. Pericarditis or Myocarditis was associated with BNT162b2 and mRNA-1273 Vaccines
    2. Incidence has been low (<2 per 100,000), even in the highest risk groups (young males age 18 to 25 years)
    3. lane (2022) bmj open 12(5): e059223 [PubMed]
    4. wong (2022) lancet 399(10342): 2191-9 [PubMed]
    5. abraham (2022) Vaccine 40(32): 4663-71 [PubMed]