Pharm
Streptomycin
search
Streptomycin
See Also
Aminoglycoside
Indications
Active Tuberculosis Treatment
Used together with multiple other agents, typically 4 drug regimens
Contraindications
Pregnancy
Mechanism
See
Aminoglycoside
Streptomycin is an
Aminoglycoside
antibiotic derived from Streptomyces griseus
Dosing
Tuberculosis
Combination Therapy
See
Active Tuberculosis Treatment
Adults
Give 15 mg/kg (maximum 1 gram) IV or IM daily
Older adults (age >60 years)
Give 10 mg/kg (maximum 750 mg) IV or IM daily
Children
Give 20 to 40 mg/kg (maximum 1 gram) IM daily (FDA approved) OR
Give 15 mg/kg (maximum 1 gram) IM daily (off label)
Adverse Effects
See
Aminoglycoside
Aminoglycoside
s are associated with risk of
Ototoxicity
and nephrotoxicity (FDA black box warning)
See
Aminoglycoside
for risk factors
Safety
Pregnancy Category D
Considered safe in
Lactation
Monitoring (baseline and monthly)
Audiogram
Renal Function
Vestibular Testing
Rhomberg testing
Resources
Streptomycin Injection Solution (DailyMed)
https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=abd1f64e-4283-4370-aae8-3666316aa36e
Type your search phrase here