Myocardium

Left Ventricular Noncompaction

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Left Ventricular Noncompaction, Noncompaction Cardiomyopathy, Left Ventricular Noncompaction Cardiomyopathy

  • Epidemiology
  1. Uncommon congenital Cardiomyopathy (<1% of population)
  • Pathophysiology
  1. Disordered in-utero development of mature heart Muscle
    1. Increased trabeculation of Myocardium
    2. Development of increased intertrabecular recesses within the left ventricle
  2. Results in Left Ventricular Dysfunction
    1. Heart Failure
    2. Arrhythmia
    3. Thromboembolic disease
    4. Sudden Cardiac Death
  • Findings
  1. See Congestive Heart Failure
  • Diagnosis
  1. Echocardiogram
    1. Initial, first-line test
  2. Cardiac MRI
    1. Confirms diagnosis
  • Management
  1. See Congestive Heart Failure
  2. Anticoagulation indications
    1. Atrial Fibrillation
    2. Decreased systolic function
    3. Systemic Thromboembolism or intracardiac thrombus
  • References
  1. Brieler (2017) Am Fam Physician 96(10):640-6 [PubMed]
  2. Stacey (2015) Curr Heart Fail Rep 12(1):61-7 [PubMed]