Lab

Anti-Ro Antibody

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Anti-Ro Antibody, Anti-SS-A Antibody, Anti-Ro, Anti-SSA, Anti-Sjogrens Syndrome Related Antigen A

  • Causes
  • Negative
  1. Normal
  • Causes
  • Positive (percentage refers to sensitivity)
  1. Systemic Lupus Erythematosus (40%)
    1. Associated with photosensitive skin rash
    2. Associated with pulmonary disease
    3. Associated with Lymphopenia
  2. Sjogren's Syndrome (75%)
  3. Keratoconjunctivitis Sicca Syndrome
  4. Rheumatoid Arthritis (10%)
  5. Systemic Sclerosis (5%)
  6. Drug Induced Lupus Erythematosus (<5%)
  7. Mixed Connective Tissue Disease (<5%)
  • Associated Conditions
  1. Associated with neonatal complications (Anti-SS-A crosses the placenta)
  • References
  1. Gladman in Klippel (1997) Rheumatic Diseases p. 255-6
  2. Peng in Ruddy (2001) Kelley's Rheumatology, p. 161-72
  3. Callegari (1995) Postgrad Med, 97(4):65-74 [PubMed]
  4. Lane (2002) Am Fam Physician 65(6):1073-80 [PubMed]