- See NSAID
- FDA approved indications in Adults
- Rheumatoid Arthritis
- Osteoarthritis
- Acute Gouty Arthritis
- Mild to moderate pain
- Primary Dysmenorrhea
- Migraine Headache
- Fever
- FDA approved indications in Children (age >6 months except in PDA)
- Juvenile Rheumatoid Arthritis
- Mild to moderate pain
- Fever
- Patent Ductus Arteriosus (PDA) in premature newborns (NeoProfen)
- See NSAID
- Avoid in age under 6 months old
- Ibuprofen
- Suspension: 100 mg/5ml
- Chewables: 50 mg, 100 mg
- Oral drops: 40 mg/ml
- Tablets: 100 mg, 200 mg, 300 mg, 400 mg, 600 mg, 800 mg
- Intravenous (Caldolor)
- Adults: 400 to 800 mg IV infused over 30 minutes every 6 hours as needed
- Combinations
- Duexis (Ibuprofen 800 mg and Famotidine 26.6 mg)
- Take one tablet orally up to three times daily (swallowed whole and not cut)
- FDA approved for Osteoarthritis and Rheumatoid Arthritis
- Duexis (Ibuprofen 800 mg and Famotidine 26.6 mg)
- Children older than age 6 months
- Dose: 5-10 mg/kg orally every 6 to 8 hours
- Maximum: 40 mg/kg/day up to 2400 mg/day
- See other references for NeoProfen in Patent Ductus Arteriosus (PDA)
- Adult
- See Caldolor IV dosing above
- Dose: 400 to 800 mg orally three to four times daily
- Maximum: 3200 mg/day
- Ibuprofen Analgesic ceiling is 400 mg
- Doses 600 mg and 800 mg offer little additional Analgesic benefit above the 400 mg dose
- Motov (2019) Ann Emerg Med 74(4): 530-7 +PMID:31383385 [PubMed]
- Ibuprofen (DailyMed)
- Ibuprofen (StatPearls)