- Green Tea is safe, but NOT Green Tea extract
- Avoid Green Tea extract (risk of liver toxicity)
- Genital and Perinanal Warts (Sinecatechins or Veregen 15% is FDA approved)
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General
- Conflicting data on benefits
- Various forms (capsules, Green Tea beverages)
- Potential benefits (requires additional study)
- Colorectal Cancer risk reduction
- Breast Cancer Risk Reduction
- Weight Reduction
- Cholesterol reduction
- Cardiovascular disease risk reduction
- Pregnancy (due to theororetical anti-Folate activity)
- Dosing
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Topical (15% Sinecatechins)
- Apply 0.5 cm per wart three times daily for 16 weeks
- Typical dose: 3 cups Green Tea per day (~320 mg Polyphenols)
- Most studies used between 3-5 cups/day of Green Tea
- Contact reaction (allergic or irritant)
- Gastrointestinal upset
- Hepatotoxicity (case reports)
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Drug Interactions
-
General
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Warfarin
- Possible warfarin Antagonist at high dose (due to Vitamin K)
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Drug Interactions
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OATP Inhibitor (Organic anion-transporting polypeptide inhibitor)
- Background
- Orange juice, apple juice and Grapefruit juice also inhibit the OATP transporter
- Catechins in Green Tea also inhibits the OATP transporter
- Green Tea 12 oz twice daily may have a Clinically Significant effect
- Medications affected
- Atenolol
- Nadolol
- Ciprofloxacin
- Levofloxacin
- Levothyroxine
- Statins
- Imatinib (Gleevac)
- Antiretrovirals
- References
- (2014) Presc lett 21(3)
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