• See Also
  1. Nigrovic Clinical Decision Rule
  2. Oostenbrink Clinical Decision Rule for Meningitis
  • Indications
  1. Bacterial Meningitis evaluation in children
  • Contraindications
  • Exclusion Criteria
  1. Neurosurgical history
  2. Immunosuppression
  3. CSF RBC Count >0.1 x10^6/ul
  4. Antibiotic use in last 48 hours
  • Criteria (1 point for each)
  1. CSF Gram Stain Positive for organisms
  2. CSF Protein >50 mg/dl
  3. Seizure related to current episode
  4. Purpura
  5. Irritability
  6. Serum Procalcitonin >= 0.5ng/ml
  7. Peripheral Absolute Neutrophil Count > 10,000 cells/mm3
  8. CSF Absolute Neutrophil Count >1000 cells/mm3
  • Efficacy
  1. Test Sensitivity: 100% (96-100%)
  • Interpretation
  1. Positive if presence of any of above (1 or more points)
  2. Suggests higher likelihood of Bacterial Meningitis
  • References
  1. Dubos (2009) Curr Opin Neurol 22(3): 288-93 [PubMed]