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Major Bleeding Risk With Anticoagulants

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Major Bleeding Risk With Anticoagulants

  • See Also
  1. Orbit Bleeding Risk Score
  2. HAS-BLED Score
  • Risk Factors
  • Fragility (1 point for each unless otherwise noted)
  1. Advanced Age (1 point if age>65, 2 points if age>75 years)
  2. Comorbidity and reduced functional capacity
  3. Frequent Falls
  4. Alcohol Abuse
  5. Recent surgery
  • Risk Factors
  • Comorbidity (1 point for each unless otherwise noted)
  1. Cancer (1 point or 2 points if metastatic)
  2. Diabetes Mellitus
  3. Liver Failure
  4. Renal Failure
  5. Prior Cerebrovascular Accident
  1. Anemia
  2. Antiplatelet Therapy
  3. Thrombocytopenia
  4. Poor Anticoagulant control
  5. Prior bleeding problems
  • Interpretation
  • Absolute Bleeding Risk (based on total risk points from above)
  1. Low risk (0 risk factors)
    1. Initial risk <3 months: 1.6%
    2. Later risk >3 months: 0.8%
  2. Moderate risk (1 risk factor)
    1. Initial risk <3 months: 3.2%
    2. Later risk >3 months: 1.6%
  3. High risk (2 or more risk factors)
    1. Initial risk <3 months: 12.8%
    2. Later risk >3 months: 6.5%
  • References
  1. Kearon (2012) Chest141(2 suppl):e419S-494S [PubMed]