Lab

Gamma glutamyl transferase

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Gamma glutamyl transferase, GGT

  • See Also
  1. Liver Function Test
  2. Liver Function Test Abnormality
  • Pathophysiology
  1. Membrane bound hepatic cell marker
  2. Suggests cholestasis
  3. Most sensitive, but least specific of all LFTs
  • Normal
  • 0-30 U/L
  • Increased (Elevation 3 times normal is significant)
  1. Chronic Alcoholic Hepatitis or other liver disease
  2. Liver neoplasm or metastases
  3. Nephrotic Syndrome
  4. Cholestasis
  5. Pancreatic Carcinoma
  6. Congestive Heart Failure (CHF)
  7. Sepsis
  8. Systemic Lupus Erythematosus (SLE)
  9. Medications
    1. Phenytoin
    2. Barbiturates