Pharm

Cortisone

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Cortisone

  • Indications
  • Mechanism
  1. See Systemic Corticosteroid
  2. Cortisone is a naturally occurring steroid Hormone produced in the Adrenal Gland
  3. Cortisone is hydroxylated to the active Cortisol by the enzyme 11-beta-steroid dehydrogenase
  • Medications
  1. Cortisone (Cortone) tablets 25 mg
  1. Adult: 25 to 300 mg orally daily
  2. Child (not FDA approved): 0.5 to 0.75 mg/kg/day orally divided every 8 hours
  • Pharmacokinetics
  1. Low potency
  2. Low anti-inflammatory potency
  3. Has Mineralocorticoid Activity
  4. Short Half-Life (8-12 hours)
  • Adverse Effects
  • Safety
  1. See Systemic Corticosteroid
  2. Pregnancy Category D
  3. Avoid in Lactation