Hyperplasia
Sebaceous Hyperplasia
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Sebaceous Hyperplasia
, Senile Hyperplasia, Senile Sebaceous Hyperplasia
See Also
Intraoral Sebaceous Hyperplasia
Epidemiology
Onset in middle age
Rarely occurs at
Puberty
in familial forms
Intraoral Sebaceous Hyperplasia
(
Fordyce Spots
) are seen in 1% of newborns
Pathophysiology
Composed of mature
Sebaceous Gland
s with dilated duct
Causes
Most cases idiopathic with aging
Cyclosporine
Hemodialysis
Signs
Characteristics
Pale yellow color
Soft, shiny dome-shaped
Papule
s
May be centrally umbilicated
Usually 2-4 mm in size
May appear cauliflower-like with multiple lobules
Distribution
Forehead, Cheeks, Nose
Vulva
Labs
Biopsy only lesions suspicious for
Basal Cell Carcinoma
Differential Diagnosis
Basal Cell Carcinoma
Basal cell is typically more red or pink than the yellow Sebaceous Hyperplasia
Surf
ace vessels are haphazardly positioned (under magnification)
Contrast with inter-lobular vessels only in Sebaceous Hyperplasia
Management
Biopsy if suspect
Basal Cell Carcinoma
Cosmetic removal
Shave excision
Electrodesiccation
Cryosurgery
Laser ablation
Topical bichloracetic acid
Avoid curettage due to scarring
Multiple lesions have been treated with
Accutane
(oral
Isotretinoin
)
References
Habif (1996) Dermatology, Mosby, p. 646-7
Higgins (2015) Am Fam Physician 92(7): 601-7 [PubMed]
Luba (2003) Am Fam Physician 64(3):729-38 [PubMed]
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