- See Fibric Acid Derivative
- Avoid in Serum Creatinine >=2 mg/dl
- Take 600 mg orally twice daily at 30 minutes before meals
- See Fibric Acid Derivative
- No Fibrate has been shown to reduce all cause mortality
- Gemfibrozil is the only Fibrate shown to decrease cardiovascular events
- NNT to prevent one coronary event: 46-125
- Pregnancy Category C
- Unknown safety in Lactation
- See Fibric Acid Derivative
- Avoid with specific other medications
- Statins (esp. Simvastatin)
- Dasabuvir
- Repaglinide
- Increases levels of other medications
- CYP2C8 Substrates (e.g. Montelukast, Paclitaxel, Pioglitazone)
- OATP1B1 Substrates (e.g. Ezetimibe, Glyburide, Olmesartan, Rifampin)
- Warfarin