Diffuse

Polymyositis

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Polymyositis

  • See Also
  1. Dermatomyositis
  • Types
  1. Type 1: Primary Idiopathic Polymyositis (33%)
  2. Type 2: Primary Idiopathic Dermatomyositis (25%)
  3. Type 3: Neoplasia related
  4. Type 4: Childhood disease with Vasculitis
  5. Type 5: Collagen Vascular disease related
  6. Type 6: Miscellaneous (Inclusion body, Eosinophilic)
  • Diagnostic Criteria
  1. Dermatomyositis Diagnosis
    1. Four or more findings seen in Polymyositis (below)
    2. Cutaneous findings suggestive of Dermatomyositis
  2. Polymyositis Diagnosis (4 or more criteria below)
    1. Proximal Muscle Weakness (trunk, thighs, Shoulders)
    2. Increased serum Creatine Phosphokinase or Aldolase
    3. Muscle pain on grasping or spontaneously
    4. EMG myogenic changes (see Polymyositis Evaluation)
    5. Positive anti-Jo1 Antibody
    6. Nondestructive Arthritis or Arthralgia
    7. Pathologic inflammatory signs
    8. Systemic inflammation signs
      1. Temperature over 37 C at axilla
      2. C-Reactive Protein increased
      3. Erythrocyte Sedimentation Rate >20 mm/hour
  • Differential Diagnosis
  1. See Polymyositis Differential Diagnosis
  • Evaluation
  1. See Polymyositis Evaluation
  • Management
  1. See Polymyositis Management
  • References
  1. Koler (2001) Am Fam Physician 64(9):1565-72 [PubMed]
  2. Pachman (1995) Pediatr Clin North Am 42:1071-98 [PubMed]
  3. Tanimoto (1995) J Rheumatol 22:4 [PubMed]