- Results altered by Hyperkalemia Management
- Obtain lab sample prior to intervention if possible
- Do not delay treatment in emergent Hyperkalemia
- Serum Potassium and Serum Osmolality
- Spot urine for Urine Potassium and Urine Osmolality
- Transtubular Potassium Gradient (TTPG)
- TTPG <6-8%: Renal cause of Hyperkalemia
- Hypoaldeosteronism suggested by very low TTPG
- TTPG >6-8: Extrarenal cause of Hyperkalemia
- May also be increased in Chronic Renal Failure