Glomerulus

Focal Segmental Glomerulosclerosis

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Focal Segmental Glomerulosclerosis, Focal Glomerulosclerosis, FSGS

  • See Also
  1. Nephrotic Syndrome
  • Epidemiology
  1. Accounts for one third of Nephrotic Syndrome in adults
  2. Accounts for >3% of new cases of End Stage Renal Disease
  3. Most common cause of idiopathic Nephrotic Syndrome in adults
  • Labs
  • Pathology with electron microscopy
  1. Sclerosis and hyalinosis of segments of <50% of all glomeruli
  • Signs
  1. Nephrotic Syndrome
  2. Key additional findings
    1. Hypertension
    2. Renal Insufficiency
    3. Hematuria
  • References
  1. Karnath (2007) Hosp Physician 43(10): 25-30 [PubMed]
  2. Kodner (2009) Am Fam Physician 80(10): 1129-36 [PubMed]