CD

Phencyclidine

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Phencyclidine, PCP

  • Background
  1. Class
    1. Dissociative Agent and Hallucinogen
    2. Schedule II
  2. Street Names
    1. Angel dust
    2. Hog
    3. Horse Tranquilizer
  • Pharmacokinetics
  1. PCP (2-10 mg): 3-18 hour duration
  • Signs
  • Labs
  • Differential Diagnosis
  1. See Hallucinogen
  2. Dextromethorphan Toxicity may have similar effect (and a False Positive urine tox for PCP)
  • Management
  • Toxicity
  1. See Toxin Ingestion
  2. Supportive care
  3. Consider Restraints for Violent Behavior
    1. Physical Restraints (with one-to-one monitoring)
    2. Chemical Restraints
  4. Benzodiazepines
  5. External cooling
  6. Status Epilepticus management (if Seizures occur)
  7. Dantrolene (Muscle Relaxant) Indications
    1. Severe hyperthermia
    2. Rhabdomyolysis
  • References
  1. Tagliaferro (2023) Crit Dec Emerg Med 37(1): 21-9