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Ginger

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Ginger, Zingiber officinale

  • See Also
  1. Herbal Medicine
  • Indications
  1. Uses with good supporting evidence
    1. Morning Sickness or Hyperemesis Gravidarum
    2. Postoperative Nausea or Vomiting
  2. Uses with variable evidence to support
    1. Motion Sickness
    2. Osteoartthritis
    3. Chemotherapy-Induced Nausea
  • Safety
  1. Pregnancy
    1. Mixed safety results
      1. If used in pregnancy, then use with caution and limit to first trimester
      2. Late pregnancy use is associated with bleeding, prematurity and decreased Head Circumference
    2. Effects
      1. Ginger affects Testosterone binding
      2. Ginger affects Thromboxane synthetase activity
      3. Animal studies showed increased Embryo loss
    3. References
      1. Larimore (2000) Prim Care 27(1): 35-53 [PubMed]
  1. Effective, safe and well tolerated
    1. Smith (2004) Obstet Gynecol 103:639-45 [PubMed]
  2. Dose of 250 mg qid showed benefit in 70% of cases
    1. Vutyavanich (2001) Obstet Gynecol 97:577-82 [PubMed]
  • Drug Interactions
  1. Warfarin (Coumadin) - possible interaction
  • Adverse Effects
  1. Mild gastrointestinal upset (e.g. Reflux or Diarrhea)
  • Dosing
  1. General range: 250 to 1000 mg PO daily to qid
  2. Pregnancy-induced Nausea: 250 mg PO four times daily
  • Cost
  1. Inexpensive (<$20 per month)
  • References
  1. White (2007) Am Fam Physician 75:1689-91 [PubMed]