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Collagen Supplement

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Collagen Supplement, Oral Collagen Peptide, Hydrolyzed Collagen, Collagen Hydrolysate

  • See Also
  1. Collagen
  2. Chondroitin
  3. Herbal Medicine
  • Background
  1. Highly touted fad product in 2022 marketed for many unsupported claims
  2. Costly ($100/month in 2022)
  3. Dosing is not standardized (study doses ranged from 370 mg to 12 grams/day)
  4. Evidence supports some uses (see indications below)
    1. Limited trial for 3 to 6 months may be reasonable for evidence-based indications
    2. Stop if no effect seen
  • Indications (Evidence Supported)
  1. Knee Osteoarthritis Pain
    1. Oral Collagen Peptides 10 g/day
    2. Zdzieblik (2021) Nutrients 13(2): 523 [PubMed]
  2. Skin Hydration and Elasticity
    1. Oral Collagen Peptides 4 to 10 g/day
    2. May offer no visible reduction in Wrinkles
    3. Bolke (2019) Nutrients 11(10): 2494 [PubMed]
  1. Background
    1. Supplements are composed of small Collagen fragments
  2. Type 1 Collagen
    1. Sources: Fish, cow
    2. Found in bone, tendons, ligaments and skin
  3. Type 2 Collagen
    1. Sources: Chicken cartilage
    2. Found in cartilage
  4. Type 3 Collagen
    1. Sources: cow
    2. Found in skin, blood vesels and various organs
  • Adverse Effects
  1. Gastrointestinal
  2. Skin rash (rare)
  • Drug Interactions
  1. No significant known Drug Interactions
  • Resources
  1. Mayo Clinic Q and A: Collagen and Biotin supplements
    1. https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-collagen-and-biotin-supplements/
  • References
  1. (2022) Presc Lett 29(7): 42
  2. (2024) Presc Lett 31(6): 36