Lab

Unconjugated Estriol

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Unconjugated Estriol

  • Indications
  1. Included in Triple Screen
  • Physiology
  1. Normally produced at low levels by ovaries
  2. Elevated in pregnancy
    1. Produced by placenta
    2. Precursors supplied by fetus
      1. Fetal Adrenal Glands
      2. Fetal liver
  • Increased Unconjugated Estriol
  1. Increases throughout normal pregnancy
  • Decreased Unconjugated Estriol
  1. Trisomy 21 (Down Syndrome)
  2. Trisomy 18 (Edwards Syndrome)