Lab

AmniSure ROM Test

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AmniSure ROM Test, PAMG-1 Protein Marker Test, Placental Alpha Microglobulin-1 Rapid Immunoassay

  • See Also
  1. Vaginal Fluid Ferning
  2. Premature Rupture of Membranes
  3. Vaginal Fluid pH (Nitrazine)
  4. Vaginal Pooling
  • Indications
  1. Evaluation for Premature Rupture of Membranes
  • Mechanism
  1. Placental Alpha Microglobulin-1 Rapid Immunoassay (PAMG-1 Protein Marker Assay)
  2. PAMG-1 is 1000 to 10,000 times more concetrated in amniotic fluid than in cervical or vaginal secretions
  • Technique
  1. No vaginal exam should be done prior to testing
  2. Sterile Dacron swab is placed at the posterior vaginal fornix for 1 minute
  3. Swab is placed in solvent vial for 1 minute
  4. Test strip is placed in solvent and result is available in 5 minutes
  • Efficacy
  1. Test Sensitivity: 95.7%
  2. Test Specificity: 100%
  3. Contrast with Test Sensitivity of 78.1% for combined standard methods
    1. Vaginal Fluid Ferning
    2. Vaginal Fluid pH (Nitrazine)
    3. Vaginal Pooling
  • References
  1. Ng (2013) Biomed Res Int 2013:587438 +PMID:24073412 [PubMed]