Bleed

Recurrent Miscarriage

search

Recurrent Miscarriage, Recurrent Pregnancy Loss

  • See Also
  1. First Trimester Bleeding
  • Indications for Recurrent Miscarriage evaluation
  1. Three consecutive Miscarriages
  • Causes (Idiopathic in up to 60% of cases)
  1. Recurrent first trimester pregnancy loss
    1. Chromosomal abnormality (5%)
    2. Antiphospholipid Antibody Syndrome (15%)
    3. Septate Uterus
    4. Polycystic Ovary Syndrome (40%)
  2. Recurrent Second Trimester Pregnancy Loss
    1. Chromosomal abnormality (5%)
    2. Antiphospholipid Antibody Syndrome (15%)
    3. Bicornuate Uterus
    4. Cervical incompetence (5%)
  • Management
  1. Preconception Counseling
    1. Folic Acid supplementation
    2. Rubella Vaccine
  2. Measures to be considered
    1. Low dose Aspirin
  3. Measures not found to be effective for prevention
    1. Lifestyle factors (e.g. strenuous activity)
    2. Progesterone
    3. Human Chorionic Gonadotropin
    4. Immunotherapy
  • References
  1. Rutherford (2002) Practitioner 246:342-9 [PubMed]